I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: January 26, 2022

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %
COL 1369 49 38 42 80 80 437 32% 53 4% 210 15%   154 6 10 10 20 26 27 18% 1 1% 30 19%   1215 43 28 32 60 54 410 34% 52 4% 180 15%
FIN 1833 82 56 80 136 110 598 33% 32 2% 383 21%   169 9 11 13 24 26 53 31% 1 1% 29 17%   1664 73 45 67 112 84 545 33% 31 2% 354 21%
GEO 967 30 10 31 41 37 358 37% 78 8% 112 12%   107 6 2 10 12 9 25 23% 8 7% 14 13%   860 24 8 21 29 28 333 39% 70 8% 98 11%
GER 594 20 25 18 43 43 210 35% 24 4% 93 16%   219 8 16 9 25 30 60 27% 4 2% 50 23%   375 12 9 9 18 13 150 40% 20 5% 43 11%
SWE 2528 140 68 89 157 113 770 30% 15 1% 588 23%   189 16 12 16 28 19 40 21% 1 1% 44 23%   2339 124 56 73 129 94 730 31% 14 1% 544 23%
WAS 1376 48 22 30 52 45 329 24% 56 4% 149 11%   134 8 2 10 12 12 22 16% 2 1% 17 13%   1242 40 20 20 40 33 307 25% 54 4% 132 11%
TOTAL  8667 369 219 290 509 428 2702 31% 258 3% 1535 18%   972 53 53 68 121 122 227 23% 17 2% 184 19%   7695 316 166 222 388 306 2475 32% 241 3% 1351 18%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn