I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: February 25, 2024

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %
COL 1368 51 38 42 80 81 431 32% 52 4% 574 42%   155 6 10 10 20 26 28 18% 1 1% 74 48%   1213 45 28 32 60 55 403 33% 51 4% 500 41%
FIN 1833 85 56 82 138 112 624 34% 35 2% 802 44%   169 8 12 13 25 27 54 32% 1 1% 72 43%   1664 77 44 69 113 85 570 34% 34 2% 730 44%
GEO 966 31 11 32 43 39 360 37% 78 8% 339 35%   108 7 2 10 12 9 25 23% 8 7% 44 41%   858 24 9 22 31 30 335 39% 70 8% 295 34%
GER 594 21 26 18 44 46 209 35% 26 4% 221 37%   219 8 16 9 25 31 60 27% 5 2% 102 47%   375 13 10 9 19 15 149 40% 21 6% 119 32%
SWE 2528 149 70 90 160 119 781 31% 15 1% 1223 48%   192 19 12 16 28 21 40 21% 1 1% 97 51%   2336 130 58 74 132 98 741 32% 14 1% 1126 48%
WAS 1378 52 26 31 57 53 304 22% 51 4% 636 46%   135 9 4 10 14 13 21 16% 0 0% 74 55%   1243 43 22 21 43 40 283 23% 51 4% 562 45%
TOTAL  8667 389 227 295 522 450 2709 31% 257 3% 3795 44%   978 57 56 68 124 127 228 23% 16 2% 463 47%   7689 332 171 227 398 323 2481 32% 241 3% 3332 43%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn