I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: August 5, 2020

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1369 50 36 40 76 68 434 32% 55 4%   152 6 10 10 20 25 27 18% 1 1%   1217 44 26 30 56 43 407 33% 54 4%
FIN 1833 74 54 77 131 103 571 31% 31 2%   169 9 10 13 23 25 51 30% 1 1%   1664 65 44 64 108 78 520 31% 30 2%
GEO 965 30 10 30 40 32 359 37% 78 8%   106 7 2 9 11 8 25 24% 8 8%   859 23 8 21 29 24 334 39% 70 8%
GER 595 21 24 17 41 39 213 36% 23 4%   219 8 16 9 25 28 61 28% 4 2%   376 13 8 8 16 11 152 40% 19 5%
SWE 2528 139 63 88 151 102 751 30% 15 1%   186 18 9 15 24 14 37 20% 1 1%   2342 121 54 73 127 88 714 30% 14 1%
WAS 1377 48 20 28 48 39 361 26% 59 4%   135 8 2 10 12 8 26 19% 3 2%   1242 40 18 18 36 31 335 27% 56 5%
TOTAL  8667 362 207 280 487 383 2689 31% 261 3%   967 56 49 66 115 108 227 23% 18 2%   7700 306 158 214 372 275 2462 32% 243 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn