I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: February 24, 2020

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1369 50 34 41 75 65 434 32% 55 4%   152 6 10 10 20 24 27 18% 1 1%   1217 44 24 31 55 41 407 33% 54 4%
FIN 1833 73 53 76 129 101 564 31% 31 2%   169 9 11 12 23 24 51 30% 1 1%   1664 64 42 64 106 77 513 31% 30 2%
GEO 965 29 11 29 40 31 359 37% 76 8%   106 6 2 9 11 7 25 24% 8 8%   859 23 9 20 29 24 334 39% 68 8%
GER 595 22 22 17 39 37 216 36% 23 4%   219 9 15 9 24 26 62 28% 4 2%   376 13 7 8 15 11 154 41% 19 5%
SWE 2527 137 64 86 150 99 745 29% 15 1%   182 17 9 15 24 14 37 20% 1 1%   2345 120 55 71 126 85 708 30% 14 1%
WAS 1378 45 21 28 49 36 372 27% 62 4%   135 7 2 10 12 7 26 19% 3 2%   1243 38 19 18 37 29 346 28% 59 5%
TOTAL  8667 356 205 277 482 369 2690 31% 262 3%   963 54 49 65 114 102 228 24% 18 2%   7704 302 156 212 368 267 2462 32% 244 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn