I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: October 21, 2020

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1369 50 37 40 77 70 434 32% 55 4%   152 6 10 10 20 25 27 18% 1 1%   1217 44 27 30 57 45 407 33% 54 4%
FIN 1833 76 53 78 131 104 583 32% 32 2%   169 9 10 13 23 25 52 31% 1 1%   1664 67 43 65 108 79 531 32% 31 2%
GEO 966 30 10 30 40 33 359 37% 78 8%   107 7 2 9 11 8 25 23% 8 7%   859 23 8 21 29 25 334 39% 70 8%
GER 595 21 24 17 41 40 210 35% 23 4%   219 8 16 9 25 29 61 28% 4 2%   376 13 8 8 16 11 149 40% 19 5%
SWE 2528 140 63 88 151 105 754 30% 15 1%   187 19 9 15 24 16 39 21% 1 1%   2341 121 54 73 127 89 715 31% 14 1%
WAS 1376 48 20 28 48 39 360 26% 59 4%   134 8 2 10 12 8 26 19% 3 2%   1242 40 18 18 36 31 334 27% 56 5%
TOTAL  8667 365 207 281 488 391 2700 31% 262 3%   968 57 49 66 115 111 230 24% 18 2%   7699 308 158 215 373 280 2470 32% 244 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn