I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: January 20, 2021

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1369 49 38 40 78 72 435 32% 55 4%   152 6 10 10 20 25 27 18% 1 1%   1217 43 28 30 58 47 408 34% 54 4%
FIN 1833 78 53 78 131 106 590 32% 32 2%   169 9 10 13 23 25 53 31% 1 1%   1664 69 43 65 108 81 537 32% 31 2%
GEO 966 30 11 29 40 34 359 37% 78 8%   107 6 2 9 11 8 25 23% 8 7%   859 24 9 20 29 26 334 39% 70 8%
GER 595 20 25 17 42 40 209 35% 23 4%   219 8 16 9 25 29 60 27% 4 2%   376 12 9 8 17 11 149 40% 19 5%
SWE 2528 139 65 88 153 105 756 30% 15 1%   187 18 10 15 25 16 39 21% 1 1%   2341 121 55 73 128 89 717 31% 14 1%
WAS 1376 48 21 28 49 40 350 25% 59 4%   134 8 2 10 12 8 24 18% 3 2%   1242 40 19 18 37 32 326 26% 56 5%
TOTAL  8667 364 213 280 493 397 2699 31% 262 3%   968 55 50 66 116 111 228 24% 18 2%   7699 309 163 214 377 286 2471 32% 244 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn