I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: December 2, 2022

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %
COL 1368 50 38 42 80 79 438 32% 53 4% 342 25%   154 6 10 10 20 26 28 18% 1 1% 50 32%   1214 44 28 32 60 53 410 34% 52 4% 292 24%
FIN 1833 84 55 82 137 112 614 33% 33 2% 572 31%   169 9 11 13 24 27 53 31% 1 1% 44 26%   1664 75 44 69 113 85 561 34% 32 2% 528 32%
GEO 966 30 11 31 42 38 358 37% 78 8% 193 20%   107 6 3 10 13 9 25 23% 8 7% 24 22%   859 24 8 21 29 29 333 39% 70 8% 169 20%
GER 594 21 25 18 43 45 209 35% 26 4% 138 23%   219 8 16 9 25 32 60 27% 5 2% 71 32%   375 13 9 9 18 13 149 40% 21 6% 67 18%
SWE 2528 146 70 89 159 115 774 31% 15 1% 864 34%   191 18 12 16 28 19 40 21% 1 1% 69 36%   2337 128 58 73 131 96 734 31% 14 1% 795 34%
WAS 1378 48 26 31 57 49 310 22% 52 4% 336 24%   135 8 4 10 14 13 22 16% 0 0% 43 32%   1243 40 22 21 43 36 288 23% 52 4% 293 24%
TOTAL  8667 379 225 293 518 438 2703 31% 257 3% 2445 28%   975 55 56 68 124 126 228 23% 16 2% 301 31%   7692 324 169 225 394 312 2475 32% 241 3% 2144 28%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn