I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: October 17, 2021

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %
COL 1369 48 38 42 80 78 437 32% 53 4% 168 12%   154 6 10 10 20 26 27 18% 1 1% 27 18%   1215 42 28 32 60 52 410 34% 52 4% 141 12%
FIN 1833 78 55 80 135 109 598 33% 32 2% 328 18%   169 8 11 13 24 26 53 31% 1 1% 22 13%   1664 70 44 67 111 83 545 33% 31 2% 306 18%
GEO 967 29 11 30 41 34 359 37% 78 8% 93 10%   107 5 2 10 12 8 25 23% 8 7% 12 11%   860 24 9 20 29 26 334 39% 70 8% 81 9%
GER 594 20 25 17 42 43 209 35% 24 4% 76 13%   219 8 16 9 25 30 60 27% 4 2% 42 19%   375 12 9 8 17 13 149 40% 20 5% 34 9%
SWE 2528 141 65 88 153 109 764 30% 15 1% 521 21%   189 18 10 15 25 17 40 21% 1 1% 38 20%   2339 123 55 73 128 92 724 31% 14 1% 483 21%
WAS 1376 48 22 30 52 45 331 24% 56 4% 116 8%   134 8 2 10 12 12 22 16% 2 1% 11 8%   1242 40 20 20 40 33 309 25% 54 4% 105 8%
TOTAL  8667 364 216 287 503 418 2698 31% 258 3% 1302 15%   972 53 51 67 118 119 227 23% 17 2% 152 16%   7695 311 165 220 385 299 2471 32% 241 3% 1150 15%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn