I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: April 16, 2021

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %
COL 1369 48 38 41 79 74 437 32% 53 4% 84 6%   152 6 10 10 20 25 27 18% 1 1% 20 13%   1217 42 28 31 59 49 410 34% 52 4% 64 5%
FIN 1833 77 54 78 132 107 594 32% 32 2% 222 12%   169 9 10 13 23 25 53 31% 1 1% 19 11%   1664 68 44 65 109 82 541 33% 31 2% 203 12%
GEO 966 30 11 29 40 34 359 37% 78 8% 51 5%   107 6 2 9 11 8 25 23% 8 7% 7 7%   859 24 9 20 29 26 334 39% 70 8% 44 5%
GER 595 20 25 17 42 41 209 35% 23 4% 49 8%   219 8 16 9 25 29 60 27% 4 2% 32 15%   376 12 9 8 17 12 149 40% 19 5% 17 5%
SWE 2528 140 65 88 153 105 756 30% 15 1% 367 15%   187 18 10 15 25 16 39 21% 1 1% 29 16%   2341 122 55 73 128 89 717 31% 14 1% 338 14%
WAS 1376 48 23 28 51 44 342 25% 57 4% 60 4%   134 8 2 10 12 11 24 18% 2 1% 8 6%   1242 40 21 18 39 33 318 26% 55 4% 52 4%
TOTAL  8667 363 216 281 497 405 2697 31% 258 3% 833 10%   968 55 50 66 116 114 228 24% 17 2% 115 12%   7699 308 166 215 381 291 2469 32% 241 3% 718 9%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn