I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: June 15, 2024

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %
COL 1368 51 38 42 80 81 430 31% 52 4% 623 46%   155 6 10 10 20 26 28 18% 1 1% 82 53%   1213 45 28 32 60 55 402 33% 51 4% 541 45%
FIN 1833 84 57 82 139 112 626 34% 37 2% 869 47%   185 8 14 14 28 29 56 30% 1 1% 87 47%   1648 76 43 68 111 83 570 35% 36 2% 782 47%
GEO 966 31 11 32 43 40 360 37% 78 8% 367 38%   108 7 2 10 12 10 25 23% 8 7% 49 45%   858 24 9 22 31 30 335 39% 70 8% 318 37%
GER 594 21 26 18 44 46 209 35% 26 4% 252 42%   221 8 16 9 25 31 60 27% 5 2% 109 49%   373 13 10 9 19 15 149 40% 21 6% 143 38%
SWE 2528 153 69 91 160 122 781 31% 15 1% 1308 52%   198 19 12 16 28 22 42 21% 1 1% 111 56%   2330 134 57 75 132 100 739 32% 14 1% 1197 51%
WAS 1378 52 26 31 57 53 304 22% 49 4% 693 50%   141 9 4 10 14 13 22 16% 0 0% 83 59%   1237 43 22 21 43 40 282 23% 49 4% 610 49%
TOTAL  8667 392 227 296 523 454 2710 31% 257 3% 4112 47%   1008 57 58 69 127 131 233 23% 16 2% 521 52%   7659 335 169 227 396 323 2477 32% 241 3% 3591 47%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn