I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: August 3, 2021

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %
COL 1369 48 38 42 80 77 437 32% 53 4% 134 10%   154 6 10 10 20 26 27 18% 1 1% 25 16%   1215 42 28 32 60 51 410 34% 52 4% 109 9%
FIN 1833 78 55 79 134 108 599 33% 32 2% 279 15%   169 8 11 13 24 26 53 31% 1 1% 20 12%   1664 70 44 66 110 82 546 33% 31 2% 259 16%
GEO 966 29 11 30 41 34 359 37% 78 8% 77 8%   107 5 2 10 12 8 25 23% 8 7% 10 9%   859 24 9 20 29 26 334 39% 70 8% 67 8%
GER 595 20 25 17 42 43 209 35% 23 4% 64 11%   219 8 16 9 25 30 60 27% 4 2% 39 18%   376 12 9 8 17 13 149 40% 19 5% 25 7%
SWE 2528 140 65 88 153 105 758 30% 15 1% 448 18%   188 18 10 15 25 16 39 21% 1 1% 31 16%   2340 122 55 73 128 89 719 31% 14 1% 417 18%
WAS 1376 48 22 30 52 44 332 24% 56 4% 88 6%   134 8 2 10 12 11 23 17% 2 1% 10 7%   1242 40 20 20 40 33 309 25% 54 4% 78 6%
TOTAL  8667 363 216 286 502 411 2694 31% 257 3% 1090 13%   971 53 51 67 118 117 227 23% 17 2% 135 14%   7696 310 165 219 384 294 2467 32% 240 3% 955 12%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn