I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: July 2, 2022

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU % Aged Out %
COL 1369 50 38 42 80 80 430 31% 53 4% 274 20%   154 6 10 10 20 26 28 18% 1 1% 42 27%   1215 44 28 32 60 54 402 33% 52 4% 232 19%
FIN 1833 84 55 81 136 111 610 33% 32 2% 478 26%   169 9 11 13 24 27 53 31% 1 1% 38 22%   1664 75 44 68 112 84 557 33% 31 2% 440 26%
GEO 966 29 11 31 42 37 358 37% 78 8% 146 15%   107 6 3 10 13 9 25 23% 8 7% 17 16%   859 23 8 21 29 28 333 39% 70 8% 129 15%
GER 594 20 25 18 43 44 210 35% 26 4% 115 19%   219 8 16 9 25 31 60 27% 5 2% 61 28%   375 12 9 9 18 13 150 40% 21 6% 54 14%
SWE 2528 145 68 89 157 115 768 30% 16 1% 720 28%   190 16 12 16 28 19 39 21% 1 1% 57 30%   2338 129 56 73 129 96 729 31% 15 1% 663 28%
WAS 1377 48 25 30 55 48 315 23% 53 4% 227 16%   135 8 3 10 13 13 22 16% 1 1% 27 20%   1242 40 22 20 42 35 293 24% 52 4% 200 16%
TOTAL  8667 376 222 291 513 435 2691 31% 258 3% 1960 23%   974 53 55 68 123 125 227 23% 17 2% 242 25%   7693 323 167 223 390 310 2464 32% 241 3% 1718 22%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn