I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: December 5, 2019

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1370 50 35 40 75 65 435 32% 55 4%   152 6 10 10 20 24 27 18% 1 1%   1218 44 25 30 55 41 408 33% 54 4%
FIN 1833 72 53 76 129 99 560 31% 31 2%   169 9 11 12 23 24 51 30% 1 1%   1664 63 42 64 106 75 509 31% 30 2%
GEO 965 28 11 29 40 31 359 37% 76 8%   106 6 2 9 11 7 25 24% 8 8%   859 22 9 20 29 24 334 39% 68 8%
GER 595 22 22 17 39 37 215 36% 23 4%   219 9 15 9 24 26 62 28% 4 2%   376 13 7 8 15 11 153 41% 19 5%
SWE 2527 135 64 86 150 99 744 29% 15 1%   182 17 9 15 24 14 37 20% 1 1%   2345 118 55 71 126 85 707 30% 14 1%
WAS 1377 44 20 28 48 35 374 27% 62 5%   135 6 2 10 12 7 26 19% 3 2%   1242 38 18 18 36 28 348 28% 59 5%
TOTAL  8667 351 205 276 481 366 2687 31% 262 3%   963 53 49 65 114 102 228 24% 18 2%   7704 298 156 211 367 264 2459 32% 244 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn