Persistent Confirmed Islet Autoimmunity	Type 1 Diabetes	Combined	
Laboratory	Analyte	Case	Control	Case + Control	Case	Control	Case + Control	Case	Control	Case + Control	
Dietary Biomarkers	Ascorbic Acid	381	1097	1478	105	327	432	486	1424	1910	
	Carotenoids	384	1102	1486	106	331	437	490	1433	1923	
	Cholesterol	384	1103	1487	106	331	437	490	1434	1924	
	Fatty Acids	401	1185	1586	111	335	446	512	1520	2032	
	Tocopherols	384	1103	1487	106	331	437	490	1434	1924	
	Vitamin D	410	1218	1628	113	341	454	523	1559	2082	
Gene Expression	mRNA	175	166	341	63	63	126	238	229	467	
Metabolomics	Lipidomics	414	1234	1648	113	341	454	527	1575	2102	
	Primary Metabolites	414	1234	1648	113	341	454	527	1575	2102	
Microbiome	Nasal Swabs - 16S	166	159	325	15	15	30	181	174	355	
	Nasal Swabs - Cultured Virome	175	167	342	16	16	32	191	183	374	
	Nasal Swabs - ITS	175	167	342	16	16	32	191	183	374	
	Nasal Swabs - Primary Virome	175	167	342	16	16	32	191	183	374	
	Nasal Swabs - WGS	148	144	292	14	14	28	162	158	320	
	Plasma - Cultured Virome	415	415	830	113	114	227	528	529	1057	
	Plasma - WGS/Virome	399	399	798	104	105	209	503	504	1007	
	Stool - 16S	410	401	811	113	113	226	523	514	1037	
	Stool - Cultured Virome	404	395	799	112	112	224	516	507	1023	
	Stool - Deep WGS	82	72	154	21	1	22	103	73	176	
	Stool - ITS	383	372	755	105	104	209	488	476	964	
	Stool - Primary Virome	408	399	807	112	112	224	520	511	1031	
	Stool - WGS	401	389	790	110	110	220	511	499	1010	
SNP	SNPs	416	1242	1658	111	337	448	527	1579	2106	
Whole Genome Sequencing	Whole Genome	166	174	340	36	44	80	202	218	420