I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: February 16, 2019

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1371 46 35 38 73 59 429 31% 55 4%   152 7 10 9 19 24 27 18% 1 1%   1219 39 25 29 54 35 402 33% 54 4%
FIN 1832 76 49 75 124 95 562 31% 31 2%   169 10 10 12 22 24 52 31% 1 1%   1663 66 39 63 102 71 510 31% 30 2%
GEO 965 25 10 29 39 29 359 37% 75 8%   106 4 2 9 11 6 25 24% 7 7%   859 21 8 20 28 23 334 39% 68 8%
GER 595 21 21 16 37 33 216 36% 23 4%   219 8 15 8 23 23 62 28% 4 2%   376 13 6 8 14 10 154 41% 19 5%
SWE 2527 122 61 84 145 93 742 29% 15 1%   177 13 9 15 24 13 36 20% 1 1%   2350 109 52 69 121 80 706 30% 14 1%
WAS 1377 40 20 28 48 33 382 28% 62 5%   133 5 2 10 12 7 27 20% 3 2%   1244 35 18 18 36 26 355 29% 59 5%
TOTAL  8667 330 196 270 466 342 2690 31% 261 3%   956 47 48 63 111 97 229 24% 17 2%   7711 283 148 207 355 245 2461 32% 244 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn