I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: November 16, 2017

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1371 44 34 33 67 45 410 30% 54 4%   151 6 11 8 19 18 27 18% 1 1%   1220 38 23 25 48 27 383 31% 53 4%
FIN 1832 74 46 72 118 88 549 30% 30 2%   169 8 10 11 21 19 48 28% 1 1%   1663 66 36 61 97 69 501 30% 29 2%
GEO 964 22 11 28 39 22 358 37% 69 7%   106 3 2 9 11 5 26 25% 7 7%   858 19 9 19 28 17 332 39% 62 7%
GER 595 20 21 16 37 29 224 38% 23 4%   219 7 15 8 23 21 67 31% 4 2%   376 13 6 8 14 8 157 42% 19 5%
SWE 2526 117 58 81 139 83 734 29% 15 1%   171 12 8 14 22 12 33 19% 1 1%   2355 105 50 67 117 71 701 30% 14 1%
WAS 1379 38 18 26 44 27 409 30% 63 5%   133 5 2 9 11 7 27 20% 4 3%   1246 33 16 17 33 20 382 31% 59 5%
TOTAL  8667 315 188 256 444 294 2684 31% 254 3%   949 41 48 59 107 82 228 24% 18 2%   7718 274 140 197 337 212 2456 32% 236 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn