I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: April 16, 2019

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1370 49 36 38 74 60 428 31% 55 4%   152 6 11 9 20 24 27 18% 1 1%   1218 43 25 29 54 36 401 33% 54 4%
FIN 1832 76 49 75 124 95 558 30% 31 2%   169 10 10 12 22 24 52 31% 1 1%   1663 66 39 63 102 71 506 30% 30 2%
GEO 966 24 11 29 40 29 359 37% 76 8%   106 4 2 9 11 6 25 24% 8 8%   860 20 9 20 29 23 334 39% 68 8%
GER 595 21 21 16 37 33 216 36% 23 4%   219 8 15 8 23 23 62 28% 4 2%   376 13 6 8 14 10 154 41% 19 5%
SWE 2527 121 63 84 147 94 738 29% 15 1%   179 13 9 15 24 13 37 21% 1 1%   2348 108 54 69 123 81 701 30% 14 1%
WAS 1377 41 21 27 48 33 380 28% 62 5%   133 5 2 10 12 7 27 20% 3 2%   1244 36 19 17 36 26 353 28% 59 5%
TOTAL  8667 332 201 269 470 344 2679 31% 262 3%   958 46 49 63 112 97 230 24% 18 2%   7709 286 152 206 358 247 2449 32% 244 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn