I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: December 16, 2018

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1370 45 36 37 73 54 429 31% 55 4%   152 7 10 9 19 21 27 18% 1 1%   1218 38 26 28 54 33 402 33% 54 4%
FIN 1832 76 49 75 124 94 561 31% 31 2%   169 10 10 12 22 23 52 31% 1 1%   1663 66 39 63 102 71 509 31% 30 2%
GEO 965 25 10 29 39 28 356 37% 74 8%   106 4 2 9 11 6 25 24% 7 7%   859 21 8 20 28 22 331 39% 67 8%
GER 595 21 21 16 37 32 217 36% 23 4%   219 8 15 8 23 22 64 29% 4 2%   376 13 6 8 14 10 153 41% 19 5%
SWE 2527 123 59 84 143 92 746 30% 15 1%   176 14 8 14 22 13 36 20% 1 1%   2351 109 51 70 121 79 710 30% 14 1%
WAS 1378 40 21 27 48 33 382 28% 63 5%   133 5 2 10 12 7 27 20% 4 3%   1245 35 19 17 36 26 355 29% 59 5%
TOTAL  8667 330 196 268 464 333 2691 31% 261 3%   955 48 47 62 109 92 231 24% 18 2%   7712 282 149 206 355 241 2460 32% 243 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn