I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: January 14, 2018

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1371 46 33 34 67 46 410 30% 54 4%   151 7 10 9 19 19 27 18% 1 1%   1220 39 23 25 48 27 383 31% 53 4%
FIN 1832 74 45 73 118 89 551 30% 30 2%   169 8 10 11 21 20 50 30% 1 1%   1663 66 35 62 97 69 501 30% 29 2%
GEO 964 22 11 28 39 23 358 37% 69 7%   106 3 2 9 11 5 26 25% 7 7%   858 19 9 19 28 18 332 39% 62 7%
GER 595 20 21 16 37 29 223 37% 23 4%   219 7 15 8 23 21 67 31% 4 2%   376 13 6 8 14 8 156 41% 19 5%
SWE 2527 119 58 81 139 83 737 29% 15 1%   172 12 8 14 22 12 34 20% 1 1%   2355 107 50 67 117 71 703 30% 14 1%
WAS 1378 38 19 26 45 29 407 30% 63 5%   132 5 2 9 11 7 27 20% 4 3%   1246 33 17 17 34 22 380 30% 59 5%
TOTAL  8667 319 187 258 445 299 2686 31% 254 3%   949 42 47 60 107 84 231 24% 18 2%   7718 277 140 198 338 215 2455 32% 236 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn