I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: September 17, 2019

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1370 47 35 40 75 61 433 32% 55 4%   152 6 10 10 20 24 27 18% 1 1%   1218 41 25 30 55 37 406 33% 54 4%
FIN 1833 73 53 75 128 97 561 31% 31 2%   169 9 11 12 23 24 52 31% 1 1%   1664 64 42 63 105 73 509 31% 30 2%
GEO 966 27 11 29 40 30 359 37% 76 8%   106 5 2 9 11 7 25 24% 8 8%   860 22 9 20 29 23 334 39% 68 8%
GER 595 21 22 16 38 36 215 36% 23 4%   219 8 15 8 23 25 62 28% 4 2%   376 13 7 8 15 11 153 41% 19 5%
SWE 2527 131 65 85 150 97 742 29% 15 1%   180 15 9 15 24 14 37 21% 1 1%   2347 116 56 70 126 83 705 30% 14 1%
WAS 1376 44 21 27 48 34 375 27% 62 5%   134 6 2 10 12 7 26 19% 3 2%   1242 38 19 17 36 27 349 28% 59 5%
TOTAL  8667 343 207 272 479 355 2685 31% 262 3%   960 49 49 64 113 101 229 24% 18 2%   7707 294 158 208 366 254 2456 32% 244 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn