I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: September 17, 2017

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1372 44 33 33 66 44 410 30% 54 4%   151 6 11 8 19 18 27 18% 1 1%   1221 38 22 25 47 26 383 31% 53 4%
FIN 1832 73 46 71 117 84 544 30% 29 2%   169 7 9 11 20 19 47 28% 1 1%   1663 66 37 60 97 65 497 30% 28 2%
GEO 964 23 11 28 39 22 358 37% 69 7%   106 3 2 9 11 5 26 25% 7 7%   858 20 9 19 28 17 332 39% 62 7%
GER 595 20 21 16 37 29 224 38% 23 4%   219 7 15 8 23 21 67 31% 4 2%   376 13 6 8 14 8 157 42% 19 5%
SWE 2525 116 59 79 138 82 732 29% 15 1%   171 10 9 13 22 12 31 18% 1 1%   2354 106 50 66 116 70 701 30% 14 1%
WAS 1379 37 18 25 43 26 411 30% 63 5%   133 5 2 9 11 6 27 20% 4 3%   1246 32 16 16 32 20 384 31% 59 5%
TOTAL  8667 313 188 252 440 287 2679 31% 253 3%   949 38 48 58 106 81 225 24% 18 2%   7718 275 140 194 334 206 2454 32% 235 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn