I.2
TEDDY
Enrollment, Endpoints and Retention
Data current as of: July 20, 2019

  Overall   FDR   GEN POP
  # Persist Conf AB   # Persist Conf AB   # Persist Conf AB  
Clinical
Center
Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %   Enrolled 1 2 3 2+ AB
Persist
Conf
T1D Withdrawn % LTFU %
COL 1370 48 35 39 74 61 432 32% 55 4%   152 6 10 10 20 24 27 18% 1 1%   1218 42 25 29 54 37 405 33% 54 4%
FIN 1832 76 50 75 125 96 561 31% 31 2%   169 9 11 12 23 24 52 31% 1 1%   1663 67 39 63 102 72 509 31% 30 2%
GEO 966 26 11 29 40 29 359 37% 76 8%   106 5 2 9 11 6 25 24% 8 8%   860 21 9 20 29 23 334 39% 68 8%
GER 595 21 22 16 38 34 215 36% 23 4%   219 8 15 8 23 23 62 28% 4 2%   376 13 7 8 15 11 153 41% 19 5%
SWE 2527 125 64 84 148 96 741 29% 15 1%   180 14 9 15 24 14 37 21% 1 1%   2347 111 55 69 124 82 704 30% 14 1%
WAS 1377 43 21 27 48 34 375 27% 62 5%   134 6 2 10 12 7 26 19% 3 2%   1243 37 19 17 36 27 349 28% 59 5%
TOTAL  8667 339 203 270 473 350 2683 31% 262 3%   960 48 49 64 113 98 229 24% 18 2%   7707 291 154 206 360 252 2454 32% 244 3%

Deceased subjects are included in Withdrawn column
% = Percent of Enrolled
Sites CHP and NBD have enrolled 9 subjects (7 and 2 respectively) - both subjects for NBD have withdrawn